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Erectile Dysfunction

Erection problems (impotence) are very common, particularly in men over 40.

Most men occasionally fail to get or keep an erection. This is usually due to stress, tiredness, anxiety or drinking too much alcohol, and it’s nothing to worry about.

If it happens more often, it may be caused by physical or emotional problems.

Physical causes Possible cause Treatment Narrowing of penis blood vessels, high blood pressure, high cholesterol medicine to lower blood pressure, statins to lower cholesterol Hormone problems hormone replacement – for example, testosterone Side effects of prescribed medication change to medicine following discussion with GP You may also be asked to make lifestyle changes.

Do lose weight if you’re overweight stop smoking eat a healthy diet exercise daily try to reduce stress and anxiety

Don’t cycle for a while (if you cycle more than 3 hours a week) drink more than 14 units of alcohol a week

  • Side Effects

    Possible side effects

    Like all medicines, this medicine can cause side effects, although not everybody gets them. These effects are normally mild to moderate in nature.

    If you experience any of the following side effects stop using the medicine and seek medical help immediately:

    allergic reactions including rashes (frequency uncommon). chest pain – do not use nitrates but seek immediate medical assistance (frequency uncommon). priapism, a prolonged and possibly painful erection after taking CIALIS (frequency rare). If you have such an erection, which lasts continuously for more than 4 hours you should contact a doctor immediately. sudden loss of vision (frequency rare). Other side effects have been reported:

    Common (seen in 1 to 10 in every 100 patients)

    headache, back pain, muscle aches, pain in arms and legs, facial flushing, nasal congestion, and indigestion. Uncommon (seen in 1 to 10 in every 1,000 patients)

    dizziness, stomach ache, feeling sick, being sick (vomiting), reflux, blurred vision, eye pain, difficulty in breathing, presence of blood in urine, prolonged erection, pounding heartbeat sensation, a fast heart rate, high blood pressure, low blood pressure, nose bleeds, ringing in the ears, swelling of the hands, feet or ankles and feeling tired. Rare (seen in 1 to 10 in every 10,000 patients)

    fainting, seizures and passing memory loss, swelling of the eyelids, red eyes, sudden decrease or loss of hearing, hives (itchy red welts on the surface of the skin), penile bleeding, presence of blood in semen and increased sweating. Heart attack and stroke have also been reported rarely in men taking CIALIS. Most of these men had known heart problems before taking this medicine.

    Partial, temporary, or permanent decrease or loss of vision in one or both eyes has been rarely reported.

  • Those who have taken the drug

    TreatmentNFullPharma

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  • Cautions

    If you have a medical condition then inform your doctor. This includes a physical examination, a laboratory test and a retina study.

    Do not use CIALIS if you have ever had a heart attack or stroke, or if you have an eye condition such as retinitis pigmentosa. CIALIS may lead to serious side effects. Some of these side effects include some rare inherited diseases (such as retinitis pigmentosa), sudden loss of hearing, feeling unwell, and a slow heartbeat. Some of the rare side effects include increased blood pressure, heart attack, stroke and heart failure.

  • Interactions

    A. Top Drug-Drug Interactions:

    1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

    2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

    3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

    Other Drug-Drug interactions:

    • Ketoconazole, itraconazole (used to manage fungal infection)
    • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
    • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
    • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
    • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

    B. Drug-Food Interactions:

    Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

    1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
    2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
    3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
    4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
    All forms of Cialis are safe and effective in individuals who are allergic to it. If you are experiencing an interaction with any of the ingredients in this leaflet, please call our doctor or visit the leaflet.Cialis is an anti-fungal and may enhance the blood pressure-lowering effects of certain anti-fungals.

    C. Contraindications:

    Cialis and alpha-blockers can interact with certain conditions, including:

    • High blood pressure: High blood pressure can riskyy affect blood flow to the penis.
    • Fluid retention: The development of fluid retention, a condition that may worsen fasting or orthostatic hypotension, may occur. If you have any of the following conditions, you should avoid Cialis.
    • Heart attack: Maintaining a balanced diet in response to variations on the symptoms experienced by individuals with an attack of chest pain or other cardiovascular problems can delay the onset or duration of treatment.

    NEW YORK, May 12 -- In a report by the New York Post-Guides, published in December, the drug maker has found that men with erectile dysfunction in the U. S. are three times more likely to die from the disease, compared with non-insured men.

    The drug maker, Lilly, has launched a $1.6 billion investment in the U. to increase its U. sales of Viagra, Lilly's No. 2 drug. The company will also give away a Viagra-specific version of its erectile dysfunction drug, Eli Lilly & Co.'s Cialis.

    The company has also introduced a product in the U. S., Lilly's third-to-fourth-line antidepressant for impotence. Viagra has been the company's No. 1 drug in the U. since it was introduced in 1998. In addition, Lilly has launched an impotence drug, Lilly's second-to-fourth-line antidepressant, Cialis. Lilly says the company is working with its U. drug sales representative to develop a new product that is more effective and cheaper than Viagra. The company said it will also invest $500 million in the U. market for Cialis.

    The company will have an annual U. sales of about $3.1 billion. The company will have about $1.9 billion in net sales, including about $1.5 billion in the U. S., according to the company. Lilly said it will spend $4.8 billion on marketing and sales related to the product and $4.6 billion on marketing, sales and sales related to Cialis.

    In addition to Viagra, the company will use a variety of other drugs and products to treat a variety of medical conditions, including erectile dysfunction, cancer, diabetes and Parkinson's disease.

    The company has spent more than $8 billion in the U. to promote the drug and has more than 1,000 Web sites advertising Viagra.

    The company said the company will also spend about $500 million to promote the erectile dysfunction drug, Cialis. Lilly said the U. sales will be about $3 billion, up from about $1.7 billion a year earlier.

    The company says the drug maker will have $1.4 billion in total net sales to be spent on the product and $500 million in total sales for the U. market, for a total of about $1.8 billion.

    The U. market for Cialis is about $1.8 billion, and Lilly has more than 4.5 million sales a year.

    The drug maker says there are no U. sales of the drug, and there is a 30 percent market share.

    Lilly's shares closed at around $11.23 on the New York Stock Exchange on Dec. 16. (SNS)

    Read More

    The drug maker has already announced that it will invest $500 million in the U.

    Lilly said on Monday that the company's share price rose to $30.45 a share to $31.35. On Jan.

    Interactions

    A. Top Drug-Drug Interactions:

    1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

    2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

    3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

    Other Drug-Drug interactions:

    • Ketoconazole, itraconazole (used to manage fungal infection)
    • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
    • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
    • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
    • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

    B. Drug-Food Interactions:

    Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

    1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
    2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
    3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
    4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
    Chesky

    C. Preventative Measures

    If you take Cialis with the following medications:

    • Sildenafil (Viagra) is a prescription medication for treating high blood pressure, providing extended daily blood pressure support for patients with low blood pressure. The medication works by increasing the flow of blood to the penis, helping to control blood pressure when you need it.
    • Orlistat ( Ozempic) is a meibomini-type weight-loss product that combines lusagnantral and semagalactday hormones to improve skin barrier function and weight loss in people with obesity.

    D. Use Recommendations:

    Some patients taking Cialis have experienced adverse reactions such as increased headaches, such as a headache that is severe or lasts beyond the next blood pressure lower than 5 mmHg, nausea, or dizziness, or flushing, such as a runny or stuffy nose.